Lasham, A., Herbert, M., Coppieters 't Wallant, N., Patel, R., Feng, S., Eszes, M., Cao, H., and Reid, G. (2009) A rapid and sensitive method to detect siRNA-mediated mRNA cleavage in vivo using 5'RACE and a molecular beacon probe. Nucleic Acids Research 2009

Patel, R., Coppieters‘t Wallant, N., Herbert, M.H., White, D., Murison, J.G. and Reid, G. (2009) The potency of siRNA-mediated growth inhibition following silencing of essential genes is dependent on siRNA design and varies with target sequence. Oligonucleotides (accepted).

Reid, G., Coppieters‘t Wallant, N., Patel, R., Antonic, A., Saxon-Aliifaalogo, F., Cao, H., Webster, G. and Watson, J.D. Potent subunit-specific effects on cell growth and drug sensitivity from optimised siRNA-mediated silencing of ribonucleotide reductase. J. RNAi Gene Silenc. 5(1): 321-330, 2009.


Lin, M.K., Belanger, H., Lee, Y.J., Varkonyi-Gasic, E., Taoka, K., Miura, E., Xoconostle-Cazares, B., Gendler, K., Jorgensen, R.A., Phinney, B., Lough, T.J. and Lucas, W.J. FLOWERING LOCUS T protein may act as the long-distance florigenic signal in the cucurbits. Plant Cell 19(5):1488-1506, 2007.


Lough, T.J. and Lucas, W.J. Integrative plant biology: role of phloem long-distance macromolecular trafficking. Ann. Rev. Plant Biol. 57:203-232, 2006.

Liefting, L.W., Andersen, M.T., Lough, T.J. and Beever, R.E. Comparative analysis of the plasmids from two isolates of "Candidatus Phytoplasma australiense". Plasmid 56(2):138-144, 2006.

Kumble, K.D. Anti-bacterial drug discovery using systems biology. Mini Rev. Med. Chem. 6(11):1275-1283, 2006.

Hall, C., Vega Flores, M., Murison, G., Crozier, K. and Crozier, P. An essential role for zebrafish Fgfrl1 during gill cartilage development. Mech. Dev. 123:925-940, 2006.

Strabala, T.J., O'Donnell, P.J., Smit, A., Ampomah-Dwamena, C., Martin, E.J., Netzler, N., Nieuwenhuizen, N.J., Quinn, B.D., Foote, H.C.C. and Hudson, K.R. Gain-of-Function Phenotypes of Many CLV3/ESR Genes, Including Four New Family Members, Correlate with Tandem Variations in the Conserved CLE Domain. Plant Physiol. 140(4):1331-1344, 2006.


Homer, C., Knight, D.A., Hananeia, L., Sheard, P., Risk, J., Lasham, A., Royds, J.A. and Braithwaite, A.W. Y-box factor YB1 controls p53 apoptotic function. Oncogene 24(56):8314-8325, 2005.


Strabala, T. J. Expressed sequence tag databases from forestry tree species. In: Molecular Genetics and Breeding of Forest Trees, (S. Kumar and M. Fladung, eds.) Haworth Press, Binghamton, NY, USA. pp 19-52, 2004.

Yoo, B.C., Kragler, F., Varkonyi-Gasic, E., Haywood, V., Archer-Evans, S., Lee, Y.M., Lough, T.J. and Lucas, W.J. A systemic small RNA signaling system in plants. Plant Cell 16(8):1979-2000, 2004.


Grigor, M.R., Phillips, J., Puthigae, S. and Strabala T.J. Sequence to systems: a pipeline for gene discovery in forestry. New Zealand Biosci. 12:5-7, 2003.

Delcayre, A., Peake, J.S., White, D.J., Yuan, S, McDonald, M.K., Liang, A., Tan, P.L. and Watson, J.D. A genome-based functional screening approach to vaccine development that combines in vitro assays and DNA immunization. Vaccine 21(23):3259-3264, 2003.

Shirtcliffe, P.M., Goldkorn, A., Weatherall, M., Tan, P.L. and Beasley, R. Pilot study of the safety and effect of intranasal delipidated acid-treated Mycobacterium vaccae in adult asthma. Respirol. 8(4):497-503, 2003.


Holland, P.M., Willis, C. R., Kanaly, S., Glaccum, M.B., Warren, A.S., Charrier, K., Murison, J.G., Derry, J.M.J., Virca, G.D., Bird, T.A. and Peschon, J.J. RIP4 is an ankyrin repeat-containing kinase essential for kerantinocyte differentiation. Curr. Biol. 12:1-20, 2002.

Zhang, G.G. Use of Plant Virus-based Expression Systems for the Production of HIV Vaccines. Molecular Farming of Plants and Animals for Human and Veterinary Medicine. Erickson et al. (eds), pp. 155-177, 2002.


Strachan, L., Murison, J.G., Prestidge, R.L., Sleeman, M.A., Watson, J.D. and Kumble, K.D. Cloning and biological activity of Epigen, a novel member of the epidermal growth factor superfamily. J. Biol. Chem. 276:18265-18271, 2001.

Skinner, M.A., Prestidge, R., Yuan, S., Strabala, T.J. and Tan, P.L.J. The ability of heat-killed Mycobacterium vaccae to stimulate a cytotoxic T-cell response to an unrelated protein is associated with a 65 kilodalton heat-shock protein. Immunol. 102:225-233, 2001.

Wiggins, P.M. High and Low Density Intracellular Water. Cell. Mol. Biol. 47:735-744, 2001.

Sleeman, M., Fraser, J., McDonald, M., Yuan, S., White, D., Grandison, P., Kumble, K.D., Watson, J.D. and Murison, J.G. Identification of a new fibroblast growth factor receptor, FGFR5. Gene 271:171-182, 2001.

Balagon, M.V., Tan, P.L.J., Prestidge, R., Collona, R.V., Abalos, R.M., Tan, E.V., Fajardo, Jr., T.T., Walsh G.P., Watson, J.D. and Walsh, D.S. Improvement in psoriasis after intradermal administration of delipidated, deglycolipidated Mycobacterium vaccae (PVAC): results of an open-label trial. Clin. Exp. Dermatol. 26(3):233-241, 2001.

Shirtcliffe, P.M., Easthope, S.E., Cheng, S., Pearce, N.E., Tan, P.L., Le Gros, G. and Beasley, R. The effect of delipidated deglycolipidated (DDMV) and heat-killed Mycobacterium vaccae in asthma. Am. J. Respir. Crit. Care. Med. 163(6):1410-1414, 2001.


Sleeman, M.A., Fraser, J.K., Murison, J.G., Kelly, S.L., Prestidge, R.L., Palmer, D.J., Watson, J.D. and Kumble, K.D. B cell-and monocyte-activating chemokine (BMAC), a novel non-ELR and alpha-chemokine. Int. Immunol. 12(5):677-689, 2000.

Abernethy, N.J., Hagan, C., Tan, P.L.J., Birchall, N.M. and Watson. J.D. The peripheral lymphoid compartment is disrupted in flaky skin mice. Immunol. Cell Biol. 78:5-12, 2000.

Abernethy, N.J., Hagan, C., Tan, P.L.J. and Watson, J.D. Dysregulated expression of CD69 and IL-2 receptor alpha and beta chains on CD8+ T lymphocytes in flaky skin mice. Immunol. Cell Biol. 78(6):596-602, 2000.

Balagon, M.V., Cellona, R.V., Walsh, D.S., Abalos, R.M., Tan, E.V., Watson, J.D., Tan, P.L. and Walsh, G.P. Improvement in psoriasis after intradermal administration of heat-killed Mycobacterium vaccae. Int. J. Dermatol. 39(1):51-58, 2000.

Perera, R.J., Rice, S., Eagleton, C., De Ath, A. and Shenk, A. The Pinus Ubiquitin Promoter: A strong constitutive promoter for gene expression in gymnosperms and angiosperms. Plant Animal Genome VIII Conference, San Diego. January 2000; W108: 26.

Sleeman, M.A., Murison, J.G., Strachan, L., Kumble, K., Glenn, M.P., McGrath, A., Grierson, A., Havukkala, I., Tan, P.L. and Watson, J.D. Gene expression in rat dermal papilla cells: analysis of 2529 ESTs. Genomics 69(2):214-224, 2000.

Sleeman, M.A., Watson, J.D. and Murison, J.G. Neonatal murine epidermal cells express a functional multidrug-resistant pump. J. Invest. Dermatol. 115(1):19-23, 2000.

Watson, J.D. The Debate on Genetic Engineering. Designer Genes. Ed. Prebble, R., pp. 22-30, 2000.

Watson, J.D. Biotechnology New Zealand – Will we miss the boat? University of Auckland Business Review. 2(1):79-86, 2000.

Lasham, A., Lindridge, E., Rudert, F., Onrust, R. and Watson, J.D. Regulation of the human fas promoter by YB-1, Puralpha and AP-1 transcription factors. Gene 252(1-2):1-13, 2000.


Havukkala, I., Glenn, M., McGrath, A., Shenk, A. and Watson, J.D. EST sequencing for tree gene discovery. Genome Diversity and Bioinformatics, FAOBMB. November/December, 61, 1999.

McQueen, F.M., Stewart, N., Crabbe, J., Robinson, E., Yeoman, S., Tan, P.L.J. and McLean, L. Magnetic resonance imaging of the wrist in early rheumatoid arthritis reveals progression of erosions despite clinical improvement. Ann. Rheum. Dis. 58:156-163, 1999.

Norris, V., Alexandre, S., Bouligand, Y., Cellier, D., Demarty, M., Grehan, G., Gouesbet, G., Guespin, J., Insinna, E., Le Sceller, L., Maheu, B., Monnier, C., Grant, N., Onoda, T., Orange, N., Oshima, A., Picton, L., Polaert, H., Ripoll, C., Thellier, M., Valleton, J-M., Verdus, M-C., Vincent, J-C., White, G. and Wiggins, P. Hypothesis: hyperstructures regulate bacterial structure and the cell cycle. Biochim. 81(8-9):915-920, 1999.

Wilsher, M.L., Hagan, C., Prestidge, R., Wells, A.U. and Murison, G. Human in vitro immune responses to Mycobacterium tuberculosis. Tubercle Lung Dis. 79(6):371-377, 1999.

Wiggins, P.M., Rowlandson, J. and Ferguson, A.B. Preservation of murine embryos in a state of dormancy at 4oC. Am. Physiol. Soc. C291-C299, 1999.

Lasham, A., Moloney, S., Hale, T., Homer, C., Zhang, Y.F., Murison, J.G., Braithwaite, A.W. and Watson, J. The Y-box-binding protein, YB1, is a potential negative regulator of the p53 tumor suppressor. J. Biol. Chem. 278(37):35516-35523, 2003.

Zhang, Y.F., Homer, C., Edwards, S.J., Hananeia, L., Lasham, A., Royds, J., Sheard, P. and Braithwaite, A.W. Nuclear localization of Y-box factor YB1 requires wild-type p53. Oncogene 22(18):2782-2794, 2003.


Rudert, F., Lindridge, E., Lasham, A., Wang, Y., Grandison, P. and Watson, J. Silencer and enhancer regions in the human CD95 (Fas/APO-1) gene with sequence similarity to the granulocyte-macrophage colony-stimulating factor promoter: binding of single strand-specific silencer factors and AP-1 and NF-AT-like enhancer factors.
DNA Cell Biol. 17(12):991-1002, 1998.

Abbott, W.G.H., Tan, P.L.J., Geursen, A., Fraser, J.D., Simpson, I.J., Yuan, S. and Skinner, M.A. TCRBV14S1 and rheumatoid arthritis revisited: Abnormalities in the percentage of transcribed TCRBV14S1 family genes in PBMC from rheumatoid arthritis patients. Scand. J. Rheumatol. 27:68-75, 1998.

McQueen, F.M., Stewart, N., Crabbe, J., Robinson, E., Yeoman, S., Tan, P.L.J. and McLean, L. Magnetic resonance imaging of the wrist in early rheumatoid arthritis reveals a high prevalence of erosions at four months after symptom onset. Ann. Rheum. Dis. 57:350-356, 1998.

Dillon, S., Griffin, F., Hart, D., Watson, J. and Baird, M. A long-lasting interferon-gamma response is induced to a single inoculation of antigen-pulsed dendritic cells. Immunol. 95(1):132-40, 1998.


Dillon, S.M., Hart, D.N.J., Abernethy, N.J., Watson, J.D. and Baird, M.A. Priming to mycobacterial antigen in vivo using antigen-pulsed antigen presenting cells generated in vitro is influenced by the dose and presence of IL-4 in APC cultures. Scand. J. Immunol. 46(1):1-9, 1997.

Ng, K.H., Aldwell, F.E., Wedlock, D.N., Watson, J.D. and Buddle, B.M. Antigen-induced interferon-gamma and interleukin-2 responses of cattle inoculated with Mycobacterium bovis. Vet. Immunol. Immunopathol. 57(1-2):59-68, 1997

Rudert, F., Wang, Y., Lindridge, E. and Watson, J.D. Apoptosis through CD95 but not a CD40/CD95 chimeric receptor is inhibited by phorbol-12-myristate-13-acteate. DNA Cell Biol. 16(2):197-205, 1997.

Skinner, M.A., Yuan, S., Prestidge, R.L., Chuk, D., Watson, J.D. and Tan, P.L.J. Immunisation with heat-killed Mycobacterium vaccae stimulates CD8+ cytotoxic T cells specific for macrophages infected with Mycobacterium tuberculosis. Infect. Immun. 65:4525-4530, 1997.

Shenk, A., Grierson, A., Havukkala, I. and Watson, J.D. Pinus radiata cDNA sequencing as a resource for tree biotechnology. IUFRO ’97 Genetics of Radiata Pine. Ed. Burdon, R.D., and Moore, J.M. FRI Bulletin 203:76-78, 1997.


Abbott, W.G.H., Fraser, J.D., Geursen, A., Skinner, M.A., Tan, P.L.J. and Marbrook, J. The influence of a recombinant-HBsAg vaccine on the repertoire of transcribed T cell receptor beta chain variable region genes in peripheral blood in humans. Vaccine 14(4):301-306, 1996.

Abbott, W.G.H., Skinner, M.A., Voss, L., Lennon, D., Tan, P.L.J., Fraser, J.D., Simpson, I.J., Ameratunga, R. and Geursen, A. Repertoire of transcribed peripheral blood T-cell-receptor beta chain variable-region genes in acute rheumatic fever. Infect. Immun. 64(7):2842-2845, 1996.

Armstrong, G.P., Whalley, G.A., Doughty, R.N., Gramble, G.D., Flett, S.M., Tan, P.L.J. and Sharpe, D.N. Left ventricular function in Scleroderma. Brit. J. Rheum. 35:983-988, 1996.

Gradl, G., Grandison, P., Lindridge, E., Wang, Y., Watson, J.D. and Rudert, F. CD95 (Fas/APO-1) receptor is phosphorylated in vitro and in vivo and constitutively associates with several proteins. Apoptosis 1996; 1:131-140, 1996.

Berridge, M.V., Tan, A.S., McKoy, K.D., Kansara, M. and Rudert, F.H. CD95 (Fas/Apo-1)-induced apoptosis results in loss of glucose transporter function. J. Immunol. 156:4092-4099, 1996.

Garrigan, K., Moroni-Rawson, P., McMurray, C., Hermans, I., Abernethy, N.J., Watson, J.D. and Ronchese, F. Functional comparison of spleen dendritic cells and dendritic cells cultured in vitro from bone marrow precursors. Blood 88(9):3508-3512, 1996.

Rudert, F.H., Visser, E., Gradl, G., Grandison, P., Shemshedini, L., Wang, Y., Grierson, A. and Watson, J.D. pLEF, a novel vector for expression of glutathione S-transferase fusion proteins in mammalian cells. Gene 169(2):281-282, 1996.

Watson, J.D. Structure and function of cytokines. Pediatrics and Perinatology: The Scientific Basis. Ed. Gluckman P. and Hayman, M., pp. 919-927, 1996.


Abbott, W.G.H., Geursen, A., Fraser, J.D., Marbrook, J., Skinner, M.A. and Tan, P.L.J. The influence of a maternal chronic hepatitis B virus infection on the repertoire of transcribed T-cell receptor beta chain variable region genes in human cord blood. Hepatology 22(4):1034-1039, 1995.

Abbott, W.G.H., Geursen, A., Peake, J.S., Simpson, I.J., Skinner, M.A. and Tan, P.L.J. Search for linkage disequilibrium between alleles in the T cell receptor alpha and beta chain loci and susceptibility to rheumatic fever. Immunol. Cell Biol. 73:369-371, 1995.

Ameratunga, R.V., Hawkins, R., Prestidge, R.L. and Marbrook, J. A high efficiency method for purification and assay of bee venom Phospholipase A2. Pathology 27(2);157-160, 1995.

Baird, M.A., Hart, D.N.J., Abernethy, N.J. and Watson, J.D. Dendritic cell presentation of PPD and 19 kDa protein of Mycobacterium tuberculosis and emergent T helper cell phenotype. Immunol. Cell Biol. 73(6):537-543, 1995.

Chuk, D., Prestidge, R.L., Tan, P.L.J. and Watson, J.D. Mycobacterium vaccae immunity in normal and immunodeficient mice. Tuberculosis in Wildlife and Domestic Animals. Ed. F.Griffin and G. de Lisle. Otago Conference Series 3:126-127, 1995.

Douglas, R. and Tan, P.L.J. A guide to the galaxy of laboratory investigations for rheumatic disease. Patient Management. 24:37-42, 1995.

Erb, K., Watson, J.D. and Le Gros, G.S. Class MHC restricted epitopes of M. bovis and M. tuberculosis as components of DNA and peptide vaccines CD8 immune responses. Tuberculosis in Wildlife and Domestic Animals. Ed. F.Griffin and G. de Lisle. Otago Conference Series 3:108-110, 1995.

Grainger, R., Hart, D.N.J., Watson, J.D. and Baird, M.A. Antigen-Pulsed, Interleukin-4-treated B cells activate primed T cells in vitro but not native T cells in vivo. Scand. J. Immunol. 42(5):517-23, 1995.

Morrissey, P.J., Charrier, K., Horovitz, D.A., Fletcher, F.A. and Watson, J.D. Analysis of the intra-epithelial lymphocyte compartment in SCID mice that received co-isogenic CD4+ T cells. Evidence that mature post-thymic CD4+ T cells can be induced to express CD8a in vivo. J. Immunol. 154(6):2678- 2686, 1995.

Ng, K.H., Watson, J.D., Prestidge, R.L. and Buddle, B.M. Cytokine mRNA expressed in tuberculin skin test biopsies from BCG-vaccinated and Mycobacterium bovis-inoculated cattle. Immunol. Cell Biol. 73:362-368, 1995.

Prestidge, R.L., Grandison, P., Chuk, D., Booth, R. and Watson, J.D. Production of the 19-kDa antigen of Mycobacterium tuberculosis in Escherichia coli and its purification. Gene 164(1):129-132, 1995.

Prestidge, R., White, D., Tan, P. and Watson, J.D. Quantitation of Mycobacterium tuberculosis by the uracil uptake assay. Tuberculosis in Wildlife and Domestic Animals. Eds Griffin F and De Lisele G. Otago Conference Series 3: 51-52, 1995.

Rudert, F., Visser, E., Forbes, L., Lindridge, E., Wang, Y. and Watson, J.D. Identification of a silencer, enhancer and a basal promoter region in the human CD95 (Fas/APO-1) gene. DNA Cell Biol. 14(11):931-937, 1995.

Simpson, I., Skinner, M.A., Geursen, A., Peake, J.S., Abbott, W.G.H., Fraser, J.D., Lockwood, C.M. and Tan, P.L.J. Peripheral blood T lymphocytes in Systemic Vasculitis: increased T cell receptor V beta 2 gene usage in microscopic polyarteritis. Clin. Exp. Immunol. 101:220-226, 1995.

Skinner, M.A., Yuan, S-N., Kim, W-M., Watson, J.D. and Tan, P.L.J. Mycobacterium vaccae as a vaccine and therapeutic agent for tuberculosis: role of natural killer cells. Tuberculosis in Wildlife and Domestic Animals. Ed. F.Griffin and G. de Lisle. Otago Conference Series 3, 123-125, 1995.

Tan, P.L.J. Rheumatoid Arthritis. An update on pathology, diagnosis, investigation and therapy. Patient Management 24:37-42, 1995.

Watson, J., Sato, T., Chuk, D., Prestidge, R.L., Erb, K., Le Gros, G.S. and Tan, P.L.J. Role of cytokines in immune responses to mycobacterial antigens. Tuberculosis in Wildlife and Domestic Animals. Ed. F.Griffin and G. de Lisle. Otago Conference Series 3:86-91, 1995.

Yang, Y., Sammar, M., Harrison, J.E.B., Lehnert, K., Print, C.G., Leung, E., Prestidge, R.L. and Krissansen, G.W. Construction and adhesive properties of a soluble MAdCAM-1-Fc chimera expressed in a baculovirus system: phylogenetic conservation of receptor-ligand interaction. Scand. J. Immunol. 42(2):235-47, 1995.


Doherty, T.M., Love, S.G., Harding, D.R.K. and Watson, J.D. Reversal of T cell unresponsiveness by augmentation of antigen-presenting cell function. Int. Immunol. 6(5):761-768, 1994.

Grabstein, K.H., Eisenman, J., Shanebeck, K., Rauch, C., Srinivasan, S., Fung, V., Beers, C., Richardson, J., Schoenborn, M.A., Ahdieh, M., Johnson, L., Alderson, M.R., Watson, J.D., Anderson, D.M. and Giri, J.G. Cloning of a T cell growth factor that interacts with the beta chain of the inteleukin-2 receptor. Science 264:965-968, 1994.

Henderson, R.A., Krissansen, G.W., Yong, Y.Y., Leung, E. and Watson, J.D. The S-subunit of murine guanine nucleotide exchange factor eIF-2B. J. Biol. Chem. 269(48):30517-30523, 1994.

McKenna, H., Birchall, N.M. and Watson, J.D. Reconstitution properties of thymus stem cells in murine fetal liver. Dev. Immunol. 2:247-256, 1994.

McQueen, F.M., Skinner, M.A., Krissansen, G.W., Robinson, E. and Tan, P.L.J. Natural killer cell function and expression of beta7 integrin in psoriatic arthritis. J. Rheumatol. 21:2266-2272, 1994.

McQueen, F.M. and Tan, P.L.J. Predicting disease severity in rheumatoid arthritis. New Zealand Med. J. 107(975):122-124, 1994.

Morrissey, P.J., McKenna, H.J., Widmer, M.B., Braddy, S., Voice, R., Charrier, K., Williams, D.E. and Watson, J.D. SLF (c-kit ligand) stimulates the in vitro growth of immature CD3-/CD4-/CD8- thymocytes. Synergy with IL-7. Cell. Immunol. 157:118-131, 1994.

Print, C.G., Leung, E., Harrison, J.E.B., Watson, J.D. and Krissansen, G.W. Cloning of a gene encoding a human leukocyte protein characterised by extensive heptad repeats. Gene. 144(2):221-228, 1994.

Rudert, F., Roos, M., Forbes, L. and Watson, J.D. Apoptosis in L929 cells expressing a CD40/Fas chimeric receptor: dissociation of stimulatory from inhibitory death signalling functions. Biochem. Biophys. Res. Commun. 204(3):1102-1110, 1994.

Skinner, M.A., Watson, L., Geursen, A. and Tan, P.L.J. Lymphocyte responses to DR1/4 restricted peptides in rheumatoid arthritis. Inhibition of responses with peptide analogs and unrelated peptides. Ann. Rheum. Dis. 53:171-177, 1994.

Yuan, S., Tan, P.L.J. and Skinner, M.A. The effect of prostaglandin E2 and indomethacin on the cytotoxic response to mycobacterial antigens. Int. J. Immunopharm. 16:525-531, 1994.